HORDB

ID: hor000354
Uniprot ID: P85797
Protein name: Allatostatin A
Gene name: NA
Organism: Apis mellifera (Honeybee)
Family: Allatostatin family
Source: animal
Expression: NA
Disease: NA
Comments: NA
Taxonomy: Apis (genus), Apini (tribe), Apinae (subfamily), Apidae (family), Apoidea (superfamily), Aculeata (infraorder), Apocrita (suborder), Hymenoptera (order), Endopterygota (cohort), Neoptera (infraclass), Pterygota (subclass), Dicondylia, Insecta (class), Hexapoda (subphylum), Pancrustacea, Mandibulata, Arthropoda (phylum), Panarthropoda, Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: NA
GO BP: GO:0007218 neuropeptide signaling pathway
GO CC: GO:0005576 extracellular region

Sequence: AYTYVSEYKRLPVYNFGI
Length: 18(59-76)
Propeptide: MRSRTSVLTSSLAFLYFFGIVGRSALAMEETPASSMNLQHYNNMLNPMVFDDTMPEKRAYTYVSEYKRLPVYNFGIGKRWIDTNDNKRGRDYSFGLGKRRQYSFGLGKRNDNADYPLRLNLDYLPVDNPAFHSQENTDDFLEEKRGRQPYSFGLGKRAVHYSGGQPLGSKRPNDMLSQRYHFGLGKRMSEDEEESSQ
Signal peptide: MRSRTSVLTSSLAFLYFFGIVGRSALA
Modification: T18 Isoleucine amide
Glycosylation: NA
Mutagenesis: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor000354_AF2.pdb

hor000354_ESM.pdb

Mass:	248688	Formula:	C105H151N23O28
Absent amino acids:	CDHMQW	Common amino acids:	Y
pI:	8.98	Basic residues:	2
Polar residues:	8	Hydrophobic residues:	6
Hydrophobicity:	-15.56	Boman Index:	-1680
Half-Life:	4.4 hour	Half-Life Yeast:	>20 hour
Half-Life E.Coli:	>10 hour	Aliphatic Index	81.11
Instability Index:	3768.33	Extinction Coefficient cystines:	5960
Absorbance 280nm:	350.59

PubMed ID: 19576913
Title: Mass Spectrometric Profiling of (Neuro)-Peptides in the Worker Honeybee, Apis Mellifera